Depuis bien longtemps, on pense que les sources de vitamine B12 sont uniquement animales et non végétales. Après quelques années de recherche, il semblerait que la spiruline soit également source de cette vitamine. Néanmoins, les études sur ce sujet sont assez controversées.
Certains articles affirment que des molécules similaires à la vitamine B12 présente dans la spiruline ont en fait été interprétées à tort comme la véritable vitamine ; d’autres affirment que la vitamine B12 présente dans la spiruline est en fait réelle et efficace.
Cette confusion a conduit à plusieurs reprises à des erreurs et à de faux rapports. Dans l’article suivant, nous allons donner un bref aperçu de la recherche actuelle sur ce sujet ; vitamine B12 dans la spiruline, info ou intox ?
Spiruline et Vitamine B12
Les produits à base d’algues suscitent un intérêt croissant en raison de leur goût agréable et de leur teneur élevée en protéines, acides aminés essentiels, vitamines et minéraux. De plus, les produits à base de spiruline sont largement commercialisés pour leur teneur élevée en vitamine B12. La spiruline est utilisée de plus en plus, notamment dans le secteur des compléments alimentaires, où elle est employée sous forme de poudre, ou consommée sous forme de comprimés.
Photo de Vita Marija Murenaite sur Unsplash.com
Avantages de la spiruline pour la santé
La spiruline est appréciée pour la présence de plusieurs minéraux, tels que le potassium, le calcium, le magnésium, le sélénium et bien d’autres encore (1). Plusieurs avantages pour la santé, qui vont de la perte de poids à la réduction de la pression artérielle en passant par l’amélioration des triglycérides plasmatiques et également des effets antioxydants, anti-inflammatoires et immuno-stimulants (2).
La vitamine B12 et les algues
La limitation de la dépendance à l’égard des aliments d’origine animale pour la vitamine B12 a nécessité la recherche de sources alimentaires alternatives, principalement végétales. De nombreux efforts ont été réalisés depuis des décennies pour éradiquer la carence en vitamine B12 chez les végans et les végétariens. Même si de très faibles quantités sont nécessaires pour atteindre l’apport adéquat (4 μg/jour pour les adultes), un approvisionnement suffisant en vitamine B12 semble encore difficile de nos jours, et les symptômes de carence sont répandus (3). Les algues sont connues pour leurs valeurs nutritionnelles et sont utilisées comme aliments/compléments alimentaires depuis longtemps (4). Les algues les plus utilisées sont la spiruline, la chlorelle et le nori.
En raison de leur riche profil nutritionnel, l’exploration de ces algues comme source potentielle de vitamine B12 a suscité un large intérêt. Alors que la nori a été reconnue et validée comme une source de vitamine B12 biodisponible (5), la position des autres algues est restée floue en tant que source de B12, en particulier la spiruline.
Études contradictoires sur la spiruline et sa teneur en vitamine B12
Photo de Alex Lvrs sur Unsplash.com
Certaines études suggèrent que la vitamine B12 contenue dans la spiruline est une pseudo forme et qu’elle n’est pas utile pour les humains (4), (8). D’un autre côté, van den Berg, Brandsen, et Sinkeldam (9) ont trouvé que la vitamine B12 de la spiruline est absorbée par des rats. Cependant, ils ont d’abord soumis les rats à un régime alimentaire déficient en vitamine B12 pendant 6 semaines ce qui n’est pas une durée suffisante pour manifester une réelle carence en vitamine B12 (10).
D’autres études sur des rats ont également montré des effets positifs (11) mais ces études sont limitées car elles ne se sont concentrées que sur les marqueurs sanguins de la vitamine B12, ce qui n’est pas forcément un bon indicateur.
Pourquoi les études se contredisent ?
L’idée que les cyanobactéries (comme la spiruline) produisent une forme biologiquement non active de la vitamine B12 suscite des préoccupations majeures dans le domaine de la science alimentaire, car les compléments alimentaires ne contenant que de la pseudo-cobalamine (pseudo-Vitamine B12) pourraient être considérés comme inadaptés en termes de biodisponibilité pour les êtres humains. Comme les consommateurs comptent sur les effets bénéfiques pour la santé des compléments alimentaires à base d’algues, cette question importante doit également être prise en compte dans le contrôle de la qualité. Si la vitamine B12 contenue dans la spiruline ne fonctionne pas, les produits à forte teneur en pseudo-cobalamine ne devraient pas être présentés aux consommateurs comme une source étiquetée de vitamine B12.
Photo de Lena_viridis sur Freepik.com
-
L’identification de la vitamine B12 est difficile
En général, la cobalamine (vitamine B12) est considérée comme un composé difficile à analyser en raison de sa structure complexe ainsi que des nombreuses vitamines et formes différentes possibles. Les bactéries utilisées dans les analyses ne font pas la distinction entre la vitamine B12 et la pseudo-vitamine B12, ce qui entraîne des résultats surestimés et faussement positifs (12, 13). Une autre raison pour laquelle nous avons des résultats différents peut être fonction des différentes souches de spiruline. Car la plupart des méthodes d’analyse indiquent des niveaux élevés de B12 active dans certaines souches (14).
Selon un article de 2022 qui utilise une technique pour séparer la forme active et non active de la vitamine B12 dans les produits à base de spiruline, la pseudo-vitamine B12 était la forme prédominante dans les compléments alimentaires étiquetés spiruline (8). Alors que la nori a été reconnue et validée comme une source de vitamine B12 biodisponible (5), la position des autres algues est restée floue en tant que source de B12, notamment de la spiruline. Ainsi, si tu as une carence en vitamine B12 ou alors que tu es végan, il est préférable que tu t’orientes vers des alternatives autres que les algues comme la spiruline car sa biodisponibilité est douteuse.
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Van den Oever, S. P., & Mayer, H. K. (2022). Biologically active or just “pseudo”-vitamin B12 as predominant form in algae-based nutritional supplements? Journal of Food Composition and Analysis, car 109, 104464. https://doi.org/10.1016/j.jfca.2022.10446
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- Madhubalaji, Chegu Krishnamurthi; Rashmi, Venkatasubbaiah; Chauhan, Vikas Singh; Shylaja, M.Dharmesh; Sarada, Ravi (2019). Improvement of vitamin B <sub/>12</sub> status with <i>Spirulina</i> supplementation in Wistar rats validated through functional and circulatory markers. Journal of Food Biochemistry, (), –. car doi:10.1111/jfbc.13038
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